Last updated on December 2014

Trial Comparing Metformin Versus Placebo in Non Alcoholic Steatohepatitis (NASH) Patients Receiving Bariatric Surgery for Obesity


Brief description of study

This is a comparison of metformin versus placebo in NASH patients receiving bariatric surgery for obesity.

Detailed Study Description

In patients receiving bariatric surgery, a preoperative liver biopsy will confirm the presence of NASH. Those patients with NASH (histologically defined according the Brunt's criteria) will be randomized to receive metformin (2 times 850 mg orally daily) or placebo for a time period of 1 year. A control liver biopsy will be performed after one year.

Clinical Study Identifier: NCT00134303

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University Hospital Ghent

Ghent, Belgium
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