Repurposing Bromocriptine for Abeta Metabolism in Alzheimer's Disease

  • STATUS
    Recruiting
  • End date
    Mar 31, 2022
  • participants needed
    10
  • sponsor
    Kyoto University
Updated on 28 July 2021
Investigator
Haruhiko Banno, MD, PhD
Primary Contact
Osaka University (4.1 mi away) Contact
+6 other location
dementia
psychiatric disorder
mini-mental state examination

Summary

To investigate the safety and efficacy of an orally administered dose of TW-012R in patients with Alzheimer's disease bearing PSEN1 (presenilin 1) mutations (PSEN1-AD), using a placebo group as a control. In addition, long-term safety will be examined in an open-label extension trial.

Details
Condition Familial Alzheimer Disease (FAD), PSEN1 Mutation, Familial Alzheimer Disease (FAD), Familial Alzheimer Disease (FAD), Familial Alzheimer Disease (FAD), Familial Alzheimer Disease (FAD), Familial Alzheimer Disease (FAD), Familial Alzheimer Disease (FAD), Familial Alzheimer Disease (FAD), Familial Alzheimer Disease (FAD), Familial Alzheimer Disease (FAD), Familial Alzheimer Disease (FAD)
Treatment placebos, bromocriptine
Clinical Study IdentifierNCT04413344
SponsorKyoto University
Last Modified on28 July 2021

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