GBM AGILE An International, Seamless Phase II/III Responsive Adaptive Randomization Platform Trial Designed To Evaluate Multiple Regimens in Newly Diagnosed and Recurrent GBM

Updated on 22 December 2020
glioblastoma multiforme
brain tumor


People with either a new diagnosis of glioblastoma or with evidence that their tumor has returned or started to grow again may be eligible. 

This trial is studying multiple treatment options, with the results of molecular testing on the tumor determining which arm(s) a person would qualify for. 

This trial is designed to "adaptively randomize" people to treatment options based on how effective the treatment appears to be based on information being collected as the trial is carried out. 

In addition to the experimental treatment options, some people enrolled to this trial may be randomized to arms that include standard of care treatment options.


Condition Glioblastoma Multiforme, Brain Cancer, Brain Tumor
Clinical Study IdentifierTX245325
Last Modified on22 December 2020


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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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