Last updated on November 2008

High-Dose Methotrexate (MTX) for Adult Acute Lymphoblastic Leukemia (ALL)

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Acute | Lymphoblastic Leukemia
  • Age: Between 25 - 64 Years
  • Gender: Male or Female
  • Other:
    Previously untreated BCR-ABL-negative ALL
    Age between 25 and 64 years
    Performance status between 0 and 3 (ECOG criteria)
    Adequate functioning of the liver (serum bilirubin level < 2.0 mg/dL); kidneys (serum
    creatinine level < 2.0 mg/dL); and heart (left ventricular ejection fraction greater
    than 50% and no severe abnormalities detected on electrocardiograms and
    Written informed consent to participate in the trial

You may not be eligible for this study if the following are true:

  • Uncontrolled active infection
    Another severe and/or life-threatening disease
    Positive for HIV antibody and/or hepatitis B surface (HBs) antigen tests
    Another primary malignancy which is clinically active and/or requires medical
    Pregnant and/or lactating women
    Past history of renal failure

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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