Bone-biomarkers of Spinal Cord Injury Patients

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    Yeungnam University Hospital
Updated on 25 January 2021
spinal cord
spinal cord disorder
spinal cord injury


Patients with spinal cord injury have a high prevalence of osteoporosis due to chronic skeletal unloading. Recently, various treatment drugs for osteoporosis have been developed. In particular, romosozumab, a sclerostin inhibitor, has been reported to have a high therapeutic effect as an inhibitor of bone resorption while promoting bone formation. However, there are a few research concerning sclerostin of spinal cord injuries patients. Therefore we want to analyze the change of sclerostin as well as factors indicating bone formation and absorption marker in spinal cord injury patient.

Condition Osteopenia, Spinal Cord Injury, Myelopathy, Trauma, Osteoporosis, Bone Diseases, Bone Resorption, Spinal Cord Injuries, Wounds, Spinal Cord Disorders
Clinical Study IdentifierNCT04403256
SponsorYeungnam University Hospital
Last Modified on25 January 2021


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Inclusion Criteria

spinal cord injury patients
Functional ambulatory category index of 3 or less

Exclusion Criteria

history of using bone absorption medication within the effective period
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