Last updated on July 2020

NCI COVID-19 in Cancer Patients NCCAPS Study


Brief description of study

This study collects blood samples, medical information, and medical images from patients who are being treated for cancer and have a positive test for SARS CoV-2, the new coronavirus that causes the disease called COVID-19. Collecting blood samples, medical information, and medical images may help researchers determine how COVID-19 affects the outcomes of patients undergoing cancer treatment and how having cancer affects COVID-19.

Detailed Study Description

PRIMARY OBJECTIVES:

I. Characterize patient factors, such as pre-existing comorbidities, cancer type and treatment, and demographic factors, associated with short- and long-term outcomes of severe acute respiratory syndrome (SARS) coronavirus 2 (COVID-19), including severity and fatality, in cancer patients undergoing treatment.

II. Describe cancer treatment modifications made in response to COVID-19, including dose adjustments, changes in symptom management, or temporary or permanent cessation.

III. Evaluate the association of COVID-19 with cancer outcomes in patient subgroups defined by clinico-pathologic characteristics.

CORRELATIVE OBJECTIVES:

I. Future correlative biomarker objectives will include assessment of the development of SARS coronavirus 2 (SARS CoV-2) antibodies, description of the trajectory of cytokine abnormalities, and genome-wide association studies to define polymorphisms associated with severe COVID-19.

II. Future correlative imaging objectives will include assessment of COVID-19 sequelae in cancer patients.

III. Collection and banking of research blood specimens and radiological images for future research.

OUTLINE

Patients undergo collection of medical information about COVID-19 symptoms, treatments/cancer treatments and outcomes, and results from laboratory tests and imaging scans performed as part of routine care for up to 2 years. Patients also undergo collection of blood samples at up to 9 times at the same times they receive routine bloodwork. Patients who are hospitalized for COVID-19 undergo collection of blood samples at up to 6 additional times.

Clinical Study Identifier: NCT04387656

Find a site near you

Start Over

Beebe Medical Center

Lewes, DE United States
  Connect »

Beebe Health Campus

Rehoboth Beach, DE United States
  Connect »

Nanticoke Memorial Hospital

Seaford, DE United States
  Connect »

Mary Bird Perkins Cancer Center

Baton Rouge, LA United States
  Connect »

Woman's Hospital

Baton Rouge, LA United States
  Connect »

Women's Cancer Care-Covington

Covington, LA United States
  Connect »

Penrose-Saint Francis Healthcare

Colorado Springs, CO United States
  Connect »

Rocky Mountain Cancer Centers-Penrose

Colorado Springs, CO United States
  Connect »

Porter Adventist Hospital

Denver, CO United States
  Connect »

Mercy Medical Center

Durango, CO United States
  Connect »

Southwest Oncology PC

Durango, CO United States
  Connect »

Saint Anthony Hospital

Lakewood, CO United States
  Connect »

Littleton Adventist Hospital

Littleton, CO United States
  Connect »

Longmont United Hospital

Longmont, CO United States
  Connect »

Parker Adventist Hospital

Parker, CO United States
  Connect »

Kootenai Medical Center

Coeur d'Alene, ID United States
  Connect »

Kootenai Cancer Center

Post Falls, ID United States
  Connect »

Kootenai Cancer Clinic

Sandpoint, ID United States
  Connect »

Reid Health

Richmond, IN United States
  Connect »

Alegent Health Mercy Hospital

Council Bluffs, IA United States
  Connect »

Mercy Medical Center-West Lakes

West Des Moines, IA United States
  Connect »

Flaget Memorial Hospital

Bardstown, KY United States
  Connect »

Saint Joseph Hospital East

Lexington, KY United States
  Connect »

Saint Joseph London

London, KY United States
  Connect »

Jewish Hospital

Louisville, KY United States
  Connect »

Jewish Hospital Medical Center South

Shepherdsville, KY United States
  Connect »

Fairview Ridges Hospital

Burnsville, MN United States
  Connect »

Cambridge Medical Center

Cambridge, MN United States
  Connect »

Mercy Hospital

Coon Rapids, MN United States
  Connect »

Unity Hospital

Fridley, MN United States
  Connect »

Abbott-Northwestern Hospital

Minneapolis, MN United States
  Connect »

Hennepin County Medical Center

Minneapolis, MN United States
  Connect »

Health Partners Inc

Minneapolis, MN United States
  Connect »

Monticello Cancer Center

Monticello, MN United States
  Connect »

New Ulm Medical Center

New Ulm, MN United States
  Connect »

Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, MN United States
  Connect »

Regions Hospital

Saint Paul, MN United States
  Connect »

United Hospital

Saint Paul, MN United States
  Connect »

Lakeview Hospital

Stillwater, MN United States
  Connect »

Ridgeview Medical Center

Waconia, MN United States
  Connect »

Rice Memorial Hospital

Willmar, MN United States
  Connect »

Freeman Health System

Joplin, MO United States
  Connect »

Mercy Hospital Joplin

Joplin, MO United States
  Connect »

Heartland Regional Medical Center

Saint Joseph, MO United States
  Connect »

Mercy Hospital South

Saint Louis, MO United States
  Connect »

Bozeman Deaconess Hospital

Bozeman, MT United States
  Connect »

Great Falls Clinic

Great Falls, MT United States
  Connect »

Community Medical Hospital

Missoula, MT United States
  Connect »

CHI Health Saint Francis

Grand Island, NE United States
  Connect »

CHI Health Good Samaritan

Kearney, NE United States
  Connect »

Midlands Community Hospital

Papillion, NE United States
  Connect »

Indu and Raj Soin Medical Center

Beavercreek, OH United States
  Connect »

Miami Valley Hospital South

Centerville, OH United States
  Connect »

Adena Regional Medical Center

Chillicothe, OH United States
  Connect »

Bethesda North Hospital

Cincinnati, OH United States
  Connect »

Mount Carmel East Hospital

Columbus, OH United States
  Connect »

Riverside Methodist Hospital

Columbus, OH United States
  Connect »

Grant Medical Center

Columbus, OH United States
  Connect »

Doctors Hospital

Columbus, OH United States
  Connect »

Miami Valley Hospital

Dayton, OH United States
  Connect »

Grady Memorial Hospital

Delaware, OH United States
  Connect »

Dublin Methodist Hospital

Dublin, OH United States
  Connect »

Armes Family Cancer Center

Findlay, OH United States
  Connect »

Blanchard Valley Hospital

Findlay, OH United States
  Connect »

Orion Cancer Care

Findlay, OH United States
  Connect »

Dayton Physicians LLC-Atrium

Franklin, OH United States
  Connect »

Dayton Physicians LLC-Wayne

Greenville, OH United States
  Connect »

Wayne Hospital

Greenville, OH United States
  Connect »

Greater Dayton Cancer Center

Kettering, OH United States
  Connect »

First Dayton Cancer Care

Kettering, OH United States
  Connect »

Kettering Medical Center

Kettering, OH United States
  Connect »

Fairfield Medical Center

Lancaster, OH United States
  Connect »

OhioHealth Mansfield Hospital

Mansfield, OH United States
  Connect »

Marietta Memorial Hospital

Marietta, OH United States
  Connect »

Knox Community Hospital

Mount Vernon, OH United States
  Connect »

Licking Memorial Hospital

Newark, OH United States
  Connect »

Newark Radiation Oncology

Newark, OH United States
  Connect »

Southern Ohio Medical Center

Portsmouth, OH United States
  Connect »

Saint Ann's Hospital

Westerville, OH United States
  Connect »

Farmington Health Center

Farmington, UT United States
  Connect »

Harrison Medical Center

Bremerton, WA United States
  Connect »

Saint Elizabeth Hospital

Enumclaw, WA United States
  Connect »

Saint Francis Hospital

Federal Way, WA United States
  Connect »

Saint Clare Hospital

Lakewood, WA United States
  Connect »

Cancer Center of Western Wisconsin

New Richmond, WI United States
  Connect »

Billings Clinic-Cody

Cody, WY United States
  Connect »

Welch Cancer Center

Sheridan, WY United States
  Connect »

Alaska Women's Cancer Care

Anchorage, AK United States
  Connect »

Anchorage Oncology Centre

Anchorage, AK United States
  Connect »

Katmai Oncology Group

Anchorage, AK United States
  Connect »

Saint Joseph Mercy Hospital

Ann Arbor, MI United States
  Connect »

Saint Joseph Mercy Brighton

Brighton, MI United States
  Connect »

Saint Joseph Mercy Canton

Canton, MI United States
  Connect »

Caro Cancer Center

Caro, MI United States
  Connect »

Saint Joseph Mercy Chelsea

Chelsea, MI United States
  Connect »

Hurley Medical Center

Flint, MI United States
  Connect »

Academic Hematology Oncology Specialists

Grosse Pointe Woods, MI United States
  Connect »

Sparrow Hospital

Lansing, MI United States
  Connect »

Hope Cancer Clinic

Livonia, MI United States
  Connect »

Saint Mary Mercy Hospital

Livonia, MI United States
  Connect »

Hope Cancer Center

Pontiac, MI United States
  Connect »

Saint Joseph Mercy Oakland

Pontiac, MI United States
  Connect »

Bhadresh Nayak MD PC-Sterling Heights

Sterling Heights, MI United States
  Connect »

Ascension Saint Joseph Hospital

Tawas City, MI United States
  Connect »

Huron Gastroenterology PC

Ypsilanti, MI United States
  Connect »

Bay Area Hospital

Coos Bay, OR United States
  Connect »

Pocono Medical Center

East Stroudsburg, PA United States
  Connect »

Carle on Vermilion

Danville, IL United States
  Connect »

Carle Cancer Center

Urbana, IL United States
  Connect »

Rush-Copley Healthcare Center

Yorkville, IL United States
  Connect »

Lowell General Hospital

Lowell, MA United States
  Connect »

Winchester Hospital

Winchester, MA United States
  Connect »

Gulfport Memorial Hospital

Gulfport, MS United States
  Connect »

Saint Francis Hospital

Greenville, SC United States
  Connect »

Saint Francis Cancer Center

Greenville, SC United States
  Connect »

Aurora Cancer Care-Grafton

Grafton, WI United States
  Connect »

Aurora BayCare Medical Center

Green Bay, WI United States
  Connect »

Aurora Cancer Care-Milwaukee

Milwaukee, WI United States
  Connect »

Aurora Sinai Medical Center

Milwaukee, WI United States
  Connect »

Aurora Cancer Care-Racine

Racine, WI United States
  Connect »

Illinois CancerCare-Bloomington

Bloomington, IL United States
  Connect »

Memorial Hospital of Carbondale

Carbondale, IL United States
  Connect »

SIH Cancer Institute

Carterville, IL United States
  Connect »

Illinois CancerCare-Carthage

Carthage, IL United States
  Connect »

Centralia Oncology Clinic

Centralia, IL United States
  Connect »

Decatur Memorial Hospital

Decatur, IL United States
  Connect »

Crossroads Cancer Center

Effingham, IL United States
  Connect »

Illinois CancerCare-Galesburg

Galesburg, IL United States
  Connect »

Illinois CancerCare-Princeton

Princeton, IL United States
  Connect »

Saint Francis Medical Center

Cape Girardeau, MO United States
  Connect »

Capital Region Southwest Campus

Jefferson City, MO United States
  Connect »

East Carolina University

Greenville, NC United States
  Connect »

NEA Baptist Memorial Hospital

Jonesboro, AR United States
  Connect »

Kaiser Permanente-Fremont

Fremont, CA United States
  Connect »

Fresno Cancer Center

Fresno, CA United States
  Connect »

Kaiser Permanente-Fresno

Fresno, CA United States
  Connect »

Kaiser Permanente-Modesto

Modesto, CA United States
  Connect »

Kaiser Permanente-Oakland

Oakland, CA United States
  Connect »

Kaiser Permanente-Redwood City

Redwood City, CA United States
  Connect »

Kaiser Permanente-Richmond

Richmond, CA United States
  Connect »

Rohnert Park Cancer Center

Rohnert Park, CA United States
  Connect »

Kaiser Permanente-Roseville

Roseville, CA United States
  Connect »

South Sacramento Cancer Center

Sacramento, CA United States
  Connect »

Kaiser Permanente-San Francisco

San Francisco, CA United States
  Connect »

Kaiser Permanente San Leandro

San Leandro, CA United States
  Connect »

Kaiser San Rafael-Gallinas

San Rafael, CA United States
  Connect »

Kaiser Permanente-Santa Rosa

Santa Rosa, CA United States
  Connect »

Kaiser Permanente Cancer Treatment Center

South San Francisco, CA United States
  Connect »

Kaiser Permanente-South San Francisco

South San Francisco, CA United States
  Connect »

Kaiser Permanente-Stockton

Stockton, CA United States
  Connect »

Kaiser Permanente-Vallejo

Vallejo, CA United States
  Connect »

Kaiser Permanente-Walnut Creek

Walnut Creek, CA United States
  Connect »

IU Health North Hospital

Carmel, IN United States
  Connect »

Sidney and Lois Eskenazi Hospital

Indianapolis, IN United States
  Connect »

Fairbanks Memorial Hospital

Fairbanks, AK United States
  Connect »

Boulder Community Hospital

Boulder, CO United States
  Connect »

Rose Medical Center

Denver, CO United States
  Connect »

Swedish Medical Center

Englewood, CO United States
  Connect »

Sky Ridge Medical Center

Lone Tree, CO United States
  Connect »

McKee Medical Center

Loveland, CO United States
  Connect »

Ingalls Memorial Hospital

Harvey, IL United States
  Connect »

Henry Ford Hospital

Detroit, MI United States
  Connect »

Weisberg Cancer Treatment Center

Farmington Hills, MI United States
  Connect »

Allegiance Health

Jackson, MI United States
  Connect »

Henry Ford West Bloomfield Hospital

West Bloomfield, MI United States
  Connect »

Saint Vincent Healthcare

Billings, MT United States
  Connect »

Rochester General Hospital

Rochester, NY United States
  Connect »

University Pointe

West Chester, OH United States
  Connect »

Bronson Battle Creek

Battle Creek, MI United States
  Connect »

Mercy Health Saint Mary's

Grand Rapids, MI United States
  Connect »

Bronson Methodist Hospital

Kalamazoo, MI United States
  Connect »

West Michigan Cancer Center

Kalamazoo, MI United States
  Connect »

Borgess Medical Center

Kalamazoo, MI United States
  Connect »

Mercy Health Mercy Campus

Muskegon, MI United States
  Connect »

Marie Yeager Cancer Center

Saint Joseph, MI United States
  Connect »

Munson Medical Center

Traverse City, MI United States
  Connect »

Metro Health Hospital

Wyoming, MI United States
  Connect »

Mercy Medical Center

Baltimore, MD United States
  Connect »

Medical Center of Baton Rouge

Baton Rouge, LA United States
  Connect »

Ochsner High Grove

Baton Rouge, LA United States
  Connect »

Ochsner Medical Center Jefferson

New Orleans, LA United States
  Connect »

Doylestown Hospital

Doylestown, PA United States
  Connect »

Virginia Cancer Institute

Richmond, VA United States
  Connect »

Shenandoah Oncology PC

Winchester, VA United States
  Connect »

Moffitt Cancer Center

Tampa, FL United States
  Connect »

Durham VA Medical Center

Durham, NC United States
  Connect »

Gibbs Cancer Center-Gaffney

Gaffney, SC United States
  Connect »

Spartanburg Medical Center

Spartanburg, SC United States
  Connect »

Sharp Memorial Hospital

San Diego, CA United States
  Connect »

Penobscot Bay Medical Center

Rockport, ME United States
  Connect »

Jefferson Hospital

Jefferson Hills, PA United States
  Connect »

Marshfield Clinic-Chippewa Center

Chippewa Falls, WI United States
  Connect »

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


Volunteer Sign-up

Sign up for our FREE service to receive email notifications when clinical trials are posted in the medical category of interest to you.