Rheumatology Patient Registry and Biorepository

  • End date
    Jun 1, 2040
  • participants needed
  • sponsor
    Yale University
Updated on 23 April 2021
connective tissue disease
sjogren's syndrome
autoimmune disease
rheumatic diseases
prednisolone acetate ophthalmic suspension
polymyalgia rheumatica
reactive arthritis
rheumatoid arthritis
giant cell arteritis
adult onset still's disease
mixed connective tissue disease
ankylosing spondylitis
antiphospholipid syndrome


To facilitate clinical, basic science, and translational research projects involving the study of rheumatic diseases.


A rheumatology biorepository will be created to permit comparative analyses between the rheumatic diseases in order to increase the understanding of disease pathogenesis. Patients diagnosed with rheumatic diseases are invited to participate in this study. These rheumatic diseases include, but are not limited to: adult onset Still's disease, ankylosing spondylitis, psoriatic arthritis, reactive arthritis, antiphospholipid syndrome, systemic lupus erythematosus, Behcet's disease, dermatomyositis, polymyositis, giant cell arteritis and other vasculitides, Lyme's disease, mixed connective tissue disease, polymyalgia rheumatica, rheumatoid arthritis, sarcoidosis, systemic sclerosis (scleroderma), Sjogren's syndrome, and undifferentiated connective tissue disease. Healthy volunteers are also invited to participate in this study.

Condition Dermatomyositis, Rheumatism, Ankylosing spondylitis, Psoriasis, Antiphospholipid Syndrome, Behcet's Syndrome, Adult Onset Still's Disease, Autoimmune disease, CONNECTIVE TISSUE DISEASE, Sicca Syndrome, Reiter's syndrome, PSORIATIC ARTHRITIS, Lyme Disease, Giant Cell Arteritis, Rheumatoid Arthritis, Scleroderma, Systemic sclerosis, Anterior uveitis, Polymyalgia Rheumatica, Myositis, Dermatosis, SYSTEMIC LUPUS ERYTHEMATOSUS, Lyme Disease Vaccine, Musculoskeletal Disease, Lymphoproliferative Disorder, Mixed Connective Tissue Disease, Xerostomia, Sarcoidosis, Arthritis, Polymyositis, Arthritis and Arthritic Pain, Polymyalgia Rheumatica (PMR), Psoriasis and Psoriatic Disorders, Rheumatoid Arthritis (Pediatric), Dermatomyositis (Connective Tissue Disease), Congenital Skin Diseases, Polymyositis (Inflammatory Muscle Disease), Arthritis and Arthritic Pain (Pediatric), Behçet Disease, Behçet Disease, Sjogren's Syndrome, Dry Mouth, Skin Conditions, Connective Tissue Diseases, Musculoskeletal Diseases, Idiopathic Inflammatory Myopathies, Lymphoproliferative disorders, Behçet Disease, Behçet Disease, Behçet Disease, Behçet Disease, rheumatic diseases, rheumatic, temporal arteritis, reactive arthritis, sarcoid, behcet's disease, progressive systemic sclerosis, Behçet Disease, Behçet Disease, Behçet Disease, Behçet Disease, Behçet Disease, Behçet Disease, Behçet Disease, Behçet Disease
Clinical Study IdentifierNCT04402086
SponsorYale University
Last Modified on23 April 2021


Yes No Not Sure

Inclusion Criteria

Age 18 years old
No chronic skin conditions
No diagnosis of a rheumatic autoimmune disease (e.g., lupus, rheumatoid arthritis)
Normal BMI

Exclusion Criteria

Unable to provide informed consent
Currently pregnant or nursing unless the study goal is to study pregnant or nursing woman
Allergies to lidocaine or epinephrine (skin biopsies)
A history of impaired wound healing (skin biopsies)
Clear my responses

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