MiniMUD Study - Unrelated Reduced Intensity Conditioning With Treosulfan for Allogeneic Stem Cell Transplantation in Patients With Hematological Malignancies

  • STATUS
    Recruiting
  • participants needed
    30
  • sponsor
    Hospices Civils de Lyon
Updated on 7 November 2020
cancer
chronic myeloid leukemia
myeloid leukemia
lymphoid leukemia
fludarabine
chronic lymphocytic leukemia
lymphoma
myelodysplastic syndromes
multiple myeloma
hodgkin's disease
myelodysplasia
carbon monoxide
cell transplantation
fungal infection
myeloablative conditioning
leukemia
gleevec
thymoglobulin
mantle cell lymphoma

Summary

In this study, treosulfan is evaluated for conditioning in allogenic stem cell transplantation. The procedure and the follow-up are the same as in standard allogenic transplant. The donor is unrelated (identical HLA). The graft is haematological peripheral blood stem cell. The conditioning with reduced intensity is: fludarabine (from day -6 to day -2), treosulfan (from day -6 to day -4) and thymoglobuline (from day -2 to day -1).

Details
Condition Hematologic Malignancy, Allogeneic transplantation
Treatment treosulfan
Clinical Study IdentifierNCT00129155
SponsorHospices Civils de Lyon
Last Modified on7 November 2020

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