Antenatal corticosteroids, particularly, betamethasone is routinely administered to pregnant women at risk for preterm delivery to improve neonatal outcomes.
Although antenatal betamethasone was shown to induce both maternal hyperglycemia and neonatal hypoglycemia, to date, there is insufficient data to establish whether treatment for maternal hyperglycemia, particularly, metformin, will decrease the risk for neonatal hypoglycemia, particularly of preterm neonates.
In the present study the investigators will examine the effect of treatment with metformin on maternal glycemic control and hypoglycemia in preterm neonates following maternal betamethasone treatment.
Condition | Pregnancy Preterm, Preterm Pregnancy, Glycemic Control, Corticosteroids Induced Hyperglycemia |
---|---|
Treatment | Metformin |
Clinical Study Identifier | NCT04332393 |
Sponsor | The Baruch Padeh Medical Center, Poriya |
Last Modified on | 25 January 2021 |
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