Last updated on June 2020

Finding the Optimal Regimen for Mycobacterium Abscessus Treatment


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Pulmonary Disease Due to Mycobacteria (Diagnosis)
  • Age: - 100 Years
  • Gender: Male or Female

Intervention Cohort Inclusion Criteria:

  • Subjects with respiratory cultures positive for M. abscessus (MABS) (sub species abscessus, sub species bolletii, or subspecies massiliense) are required to meet all 3 American Thoracic Society criteria (clinical, radiological and microbiological) for MABS pulmonary disease (PD).
  • Subjects with mixed NTM infections (slow growers + MABS) (adding ethambutol will be permitted if required by the treating physician).
  • Willingness and ability to comply with trial regimens and the study visit requirements.

Intervention cohort Exclusion Criteria:

  • Receiving active treatment for MABS within the previous 12 months, except azithromycin for participants with cystic fibrosis and bronchiectasis.
  • Healthy volunteers may not participate.
  • Pregnancy

Observation Cohort Inclusion Criteria:

  • At least one positive MABS culture
  • Willingness and ability to comply with the study visit requirements.

Observation cohort Exclusion Criteria for:

  • Receiving active treatment for MABS within the previous 12 months, except azithromycin for participants with cystic fibrosis and bronchiectasis.
  • Healthy volunteers may not participate.

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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