The United Kingdom Multiple Sclerosis Register Covid-19 Substudy

  • days left to enroll
  • participants needed
  • sponsor
    Swansea University
Updated on 23 August 2021


The aim of the study is to understand the impact of COVID-19 on People with Multiple Sclerosis in the United Kingdom.


Study objectives

  1. To identify the incidence of upper respiratory tract symptoms: fever, cough and breathing difficulties, other symptoms suggestive of COVID-19 infection, respiratory tract infections suggestive of COVID-19, and COVID-19 confirmed by laboratory testing among the UK MS population
  2. To establish if some DMDs increase the risk of COVID-19 infection
  3. To determine the incidence and effectiveness of self-isolation in the MS population. To examine the impact self-isolation has on mood, fatigue, and other routinely collected patient reported outcome measures from the MS Register.
  4. To determine the clinical outcome of respiratory tract infections, including confirmed and suspected cases of COVID-19, in terms of symptoms, time to recovery, hospital admission, requirement for ventilation, and death.
  5. To determine the longer-term impact of COVID-19 on MS, using routinely collected MS outcomes in the MS register, including impact on disability, relapses and changes in DMDs as assessed at 3 monthly intervals.
  6. To determine where people are obtaining their health information during the COVID-19 outbreak.
  7. To establish changes in DMDs prior to and as a result of symptoms related and unrelated to COVID-19

Condition *COVID-19, Radiologically Isolated Syndrome, Dermatite Atopique modérée ou grave, multiple sclerosis (ms), Covid-19, Multiple Sclerosis
Clinical Study IdentifierNCT04354519
SponsorSwansea University
Last Modified on23 August 2021


Yes No Not Sure

Inclusion Criteria

>18 and confirmed diagnosis of MS, enrolled on UK MS Register

Exclusion Criteria

None of the above
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How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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