TMS-induced Plasticity Improving Cognitive Control in OCD (TIPICCO)

  • STATUS
    Recruiting
  • participants needed
    75
  • sponsor
    VU University Medical Center
Updated on 8 December 2022
behavior therapy
transcranial magnetic stimulation
cognitive therapy
brain stimulation
Accepts healthy volunteers

Summary

Repetitive transcranial magnetic stimulation (rTMS) has been shown in several previous clinical trials to be an effective treatment for obsessive-compulsive disorder (OCD). However, the neural working mechanisms of rTMS in OCD are unknown, and the optimal stimulation sites have not yet been established. Our study aims to compare the clinical and neurobiological effects of three different rTMS stimulation protocols in OCD patients. 8 weeks of rTMS therapy will be delivered in combination with cognitive behavioural therapy. Multimodal neuroimaging will be carried out before and after treatment in order to demonstrate the neurobiological effects of the therapy.

Details
Condition Obsessive-Compulsive Disorder
Treatment Repetitive transcranial magnetic stimulation
Clinical Study IdentifierNCT03667807
SponsorVU University Medical Center
Last Modified on8 December 2022

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