Efficacy of tDCS in the Treatment of Resistant Auditory Hallucinations in Schizophrenia (TDCSHALLU)

  • STATUS
    Recruiting
  • End date
    Jan 10, 2026
  • participants needed
    44
  • sponsor
    Centre hospitalier de Ville-Evrard, France
Updated on 4 March 2022
transcranial direct current stimulation
antipsychotics
hallucinations
auditory hallucinations

Summary

the regions which are assumed to underlie the pathophysiology of schizophrenia, namely hypoactivity at the prefrontal level and pathological hyperactivity of the associative regions of the language located in the left temporoparietal region.

to assess the effuicacy of tDCS on auditory hallucinations we perfor an randomized double blind versus placebo trial. In each arms patients will receive two tDCS sessions a day during two weeks

Details
Condition Schizophrenia, Hallucinations, Refractory Schizophrenia
Treatment Transcranial Direct Current Stimulation
Clinical Study IdentifierNCT04352569
SponsorCentre hospitalier de Ville-Evrard, France
Last Modified on4 March 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Schizophrenia according to DSM-V
Refractory auditory hallucinations(despite two antipsychotics trials)
Right-handed patients
Written informed consent

Exclusion Criteria

Presence of other psychiatric disorders than schizophrenia (except addiction to tobacco or caffeine )
History of severe head trauma or coma
History of epilepsy or neurological disorder or a general medical condition
Presence of intracranial metallic objects or pacemaker
Hospitalized patients without consent
pregnant women
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