Clinical Outcomes After Acute Pulmonary Embolism (ERASE PE)

  • End date
    Dec 31, 2030
  • participants needed
  • sponsor
    University Hospital Inselspital, Berne
Updated on 4 March 2022
acute pulmonary embolism


To investigate safety and effectiveness of PE treatment according to the decision of the multi-disciplinary pulmonary embolism response team (PERT) and to define and optimize treatment indications, institutional algorithms and interventional techniques for PE.


This single-center cohort study is designed to retrospectively and prospectively collect treatment and outcome data related to patients with PE and after activation of the PERT. Treatment information and outcomes after advanced treatment modalities, including systemic thrombolysis, catheter directed thrombolysis and surgical embolectomy, will be collected.

Retrospective patient data will consist of treatment and health related outcomes of consecutive patients treated for acute and chronic PE between October 2017 and April 2020 (to assess the learning curve of the PERT) and of patients receiving surgical embolectomy between January 2001 and April 2020. The retrospective data will be derived from the local institutional dataset and will be transferred to the study database. Prospective patients will be included after May 2020.

Condition Pulmonary Embolism
Clinical Study IdentifierNCT04355975
SponsorUniversity Hospital Inselspital, Berne
Last Modified on4 March 2022


Yes No Not Sure

Inclusion Criteria

Consecutive patients with pulmonary embolism matching the criteria for treatment according to the decision of the PERT
Written informed consent

Exclusion Criteria

High probability of non-adherence to the follow up requirements
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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