Assessment of Donor Derived Cell Free DNA and Utility in Lung Transplantation

  • End date
    Sep 1, 2023
  • participants needed
  • sponsor
    Pablo Sanchez
Updated on 15 July 2021


The use of Allosure to identify and quantify circulating donor-derived cell-free DNA to quantitate allograft injury in the early post-transplant period and determine its relationship to allograft failure.


Single Center Prospective Cohort Study on De-Novo Lung Transplant recipients. AlloSure will be drawn as part of routine blood draws and sent to CareDx for analysis of dd-cfDNA. All data will be collected and stored in the hospital EMR, this will be examined with the AlloSure results to correlate outcomes.

Condition Lung Transplant Failure and Rejection
Treatment Allosure
Clinical Study IdentifierNCT04318587
SponsorPablo Sanchez
Last Modified on15 July 2021


Yes No Not Sure

Inclusion Criteria

Participant is willing and able to give informed consent for participation in the study
Male or Female, aged 18 years or above
Denovo lung transplant recipient
Ability to understand written and spoken English

Exclusion Criteria

Previous transplant or multi-organ transplant
Unable to have blood draw for medical reason
Clear my responses

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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