Namsos Anaesthesia Children Outcome Study (NACOS)

  • STATUS
    Recruiting
  • participants needed
    640
  • sponsor
    Helse Nord-Trøndelag HF
Updated on 29 January 2023
propofol
tonsillectomy
delirium
weak
sevoflurane
behavioral disturbances

Summary

Behavioral disturbances are often seen in children after anesthesia both immediately after surgery (emergence delirium) and after discharge from hospital. Persisting behavioral changes may affect emotional and cognitive development. It is known that both type of surgery and anesthetic management affect the occurrence of behavioral disturbances. Specifically, differences in occurrence were found after sevoflurane anesthesia and propofol anesthesia, two anesthetics that are generally used in practice. However, evidence is based on methodologically weak studies.

The described occurrence of behavioral disturbances in children after anesthesia is not in line with the investigators' clinical experience, and neither are the described differences in occurrence between sevoflurane anesthesia and propofol anesthesia. This study will compare emergence delirium and behavioral changes after discharge from hospital in children who had surgery for removal of their tonsils under sevoflurane anesthesia versus propofol anesthesia.

Details
Condition Emergence Delirium
Treatment Propofol, Sevoflurane
Clinical Study IdentifierNCT04292457
SponsorHelse Nord-Trøndelag HF
Last Modified on29 January 2023

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