Nitropaste in Breast Reduction

  • End date
    Dec 3, 2024
  • participants needed
  • sponsor
    Icahn School of Medicine at Mount Sinai
Updated on 3 February 2021


The purpose of this study is evaluate the effect of Nitroglycerin paste on wound healing and scarring. Previous research has shown that Nitroglycerin paste can improve the blood flow to a wound, which may be associated with better wound healing, and ultimately, better scarring.


This will be a single-center, patient-blinded, (breast) randomized trial utilizing nitroglycerin paste on their breast reduction scar. The study team aims to randomize 100 patients, or 200 breasts. Each patient will receive treatment, but the breast that received treatment will be random. This will allow for a control breast to compare to. Patients will be followed for 12 months postoperatively to observe wound healing.

Condition Gynecomastia, Gynecomastia (breast enlargement), Gynecomastia (breast enlargement) - Pediatrics, Delayed Wound Healing, delayed healing
Treatment Dermabond, Nitroglycerin Paste
Clinical Study IdentifierNCT04321967
SponsorIcahn School of Medicine at Mount Sinai
Last Modified on3 February 2021


Yes No Not Sure

Inclusion Criteria

Patients who are female and transmen
Undergoing bilateral breast reduction via Mount Sinai Plastic Surgery Clinic
Reduction must be performed via Wise incisional pattern

Exclusion Criteria

Patients who are male or transwomen
Patients who are under 18 years of age
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