The Potential of Sperm Retrieved by Micro-TESE to Fertilize Vitrified/Warmed Oocytes

  • STATUS
    Recruiting
  • End date
    Jun 30, 2022
  • participants needed
    100
  • sponsor
    Odense University Hospital
Updated on 24 January 2021

Summary

Couples referred for microdissection-TESE (m-TESE) due to Klinefelter's syndrome, maturation stop in the spermatogenesis, or failed retrieval of testicular spermatozoa by conventional techniques with needle or TruCut are included. The women are stimulated with FSH in IVF protocols and the aspirated oocytes vitrified with usual applied techniques. Fresh sperm retrieved by micro-TESE are used for fertilization of the warmed oocytes. when it is not possible to obtain testicular sperm, the couples are offered fertilization with warmed oocytes.

Fertilization, cleavage, implantation and pregnancy rates using sperm from the patients versus from sperm donors will be compared.

Details
Condition Azoospermia, Nonobstructive, Azoospermia, Nonobstructive
Clinical Study IdentifierNCT03809026
SponsorOdense University Hospital
Last Modified on24 January 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Is your age greater than or equal to 18 yrs?
Are you male?
Do you have Azoospermia, Nonobstructive?
Do you have any of these conditions: Do you have Azoospermia, Nonobstructive??
Couples referred for micro-TESE

Exclusion Criteria

None
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