Anesthesia and Cancer Study: Colon Cancer

  • STATUS
    Recruiting
  • End date
    Feb 1, 2026
  • participants needed
    792
  • sponsor
    Seoul National University Hospital
Updated on 12 May 2022
anesthesia
cancer surgery
cancer
propofol
sevoflurane
induction of anesthesia
tiva

Summary

This study investigates the influence of type of anesthesia on survival and recurrence rate in patients receiving colon cancer surgery. The participants will be allocated to either the TIVA group and the inhalation group.

Description

The effect of anesthesia on cancer recurrence and survival is controversial. According to some retrospective studies and preclinical studies, total intravenous anesthesia (TIVA) is suggested to be more favorable than inhalation anesthesia regarding cancer recurrence and survival after surgery. However, there is no randomized controlled study to determine this difference in colon cancer patients.

Details
Condition Cancer of Colon, Anesthesia
Treatment Propofol, Sevoflurane
Clinical Study IdentifierNCT04259398
SponsorSeoul National University Hospital
Last Modified on12 May 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

adults undergoing surgery to remove colon cancer

Exclusion Criteria

pregnancy
colon cancer with invasion to perineum
palliative surgery
history of diagnosis or surgery for other cancer
emergent surgery
ASA PS classification 4 and 5
refusion to participate in the study
allergy to anesthetics
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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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