Head and Neck Cancer in Children: A Retrospective Study

  • days left to enroll
  • participants needed
  • sponsor
    Assiut University
Updated on 3 February 2021
head and neck cancer
neck cancer
neck tumor


The aim of the study is to identify demographic characteristics, various histopathologies, and site preferences for each disease entity of malignant head and neck tumors in pediatric oncology patients & treatment outcomes in these patients, according to experience at South Egypt Cancer Institute which is the largest referral site in Upper Egypt.



Although head and neck masses represent a common entity in children, malignancy is uncommon. Only very limited data are available in the literature on the incidence of childhood cancer of the head and neck worldwide.

Data from the United States National Cancer Institute database suggest that the head and neck are involved in 12 % of all childhood malignancies. The most common pediatric head and neck malignancies include Non Hodgkin lymphomas, Hodgkin lymphomas, rhabdomyosarcomas, thyroid malignancies, nasopharyngeal carcinomas (NPCs), salivary gland malignancies, and neuroblastomas.

Patients & Methods:

A hospital-based study, involving Pediatric cancer patients, those diagnosed with malignant tumors of the head & neck, in the period from 2001 January till 2015 December, and received treatment at the pediatric oncology department, their medical records will be retrospectively reviewed for data collection.

Clinico-laboratory data for each hisopathologic disease entity of various head & neck malignancies will be gathered. The demographic distribution for each disease entity in accordance with gender & age, and site preferences in these disease entities will be recorded. Treatment received & treatment outcomes will be verified and absolute frequencies & relative incidence of these disease entities will be calculated.

Condition head and neck cancer, head and neck neoplasms, head and neck tumor, cancer of the head and neck
Clinical Study IdentifierNCT02557048
SponsorAssiut University
Last Modified on3 February 2021


Yes No Not Sure

Inclusion Criteria

Patients whose age less than 19 years
Patients diagnosed with a primary malignant tumor of the head & neck

Exclusion Criteria

Patients whose age more than 18 years
Patients diagnosed with a malignant disease primarily arising from the bone marrow
Patients diagnosed with tumors of the central nervous system
Patients diagnosed with retinoblastoma
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