Effects of Soft Tissue Treatment vs Mechanisms Explanation to Treat Delayed Onset Muscles Soreness Among Sport Climbers

  • End date
    Apr 30, 2022
  • participants needed
  • sponsor
    University of Turin, Italy
Updated on 10 October 2021
5 minutes
soft tissue treatment
Accepts healthy volunteers


The aim of the present research is to define the effects of short manual treatment of soft tissues compared to mechanisms explaining in Delayed Onset Muscle Soreness (DOMS) among sport climbers and to address the mechanisms of peripheral and central sensitization involved in DOMS phenomena.


Sport climbing is a growing success sport that will be debuting as an official discipline in the Tokyo 2020 Olympics game. They are used during competitions.

To practice this discipline, both dexterity in movement and extreme physical strength are needed to climb the sloping and vertical walls that are used during competitions.

The appearance of muscle pain induced by an unusual and strenuous physical activity (DOMS) is an extremely common factor in all sports activities that involves a maximum and repeated muscular effort. In the sport climbing practice this physiological phenomenon is common and occurs both in those who practice at as professional and amateur level. Numerous studies have shown that muscle pain is induced by physical activity and independent of damage to muscle fibers and classic inflammation of tissues. The phenomenon of DOMS is accompanied by hyperalgesia and allodynia during muscle contraction, these are conditions of irritation of the peripheral nervous system (SNP) and central nervous system (CNS), but today no evidence of such sensitization phenomena of the SNP and SNC has been provided. The presence of muscle pain is one of the main causes of impossibility to practice sports not only for those who practice sport climbing at a professional level, but for most amateur sportsmen. Thanks to the tools validated in the last decade, it is possible to study the involvement and awareness responses of the SNP and SNC with reliable and non-invasive techniques in the phenomenon of DOMS. Understanding the mechanisms underlying the appearance of the DOMS is today a primary priority for sports practice and for physical training for muscular effort both as a professional and amateur level.

Presence of peripheral and central sensitization in DOMS will be assessed and a three arm randomized controlled double blind multicentric study will be performed to assess the effects of treatment on peripheral tissues compared to pain mechanisms explanation. Healthy participants of both sexes will be assessed before DOMS, at 48 hours (the peak phase of symptoms) before and after treatment and at 96 hours when symptoms usually are in remission.

Condition peripheral nerve disease, Central Sensitization, myalgias, Muscle Strength, Myalgia, Central Nervous System Sensitization, muscle pains, muscular pain, Peripheral Neuropathy, pain, muscle, Muscle Pain, Muscle Soreness
Treatment Soft tissue treatment, Mechaninsms explanation, Anatomy and human upper limb functions
Clinical Study IdentifierNCT04255212
SponsorUniversity of Turin, Italy
Last Modified on10 October 2021


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Inclusion Criteria

Being explained all the associated risks and benefits of the research
Sign the written informed consent

Exclusion Criteria

Significant neck or upper limbs pain (with Numeric Pain Rating Scale [NPRS] greater than 3/10)
Recent neck or arm surgery or significant trauma in the preceding 3 months
Cancer or inflammatory disorders
Spinal cord or cauda equina signs
Widespread neurological disorders affecting the tone of upper limbs and neck muscles
Underlying diseases, such as diabetes mellitus
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