Last updated on February 2020

Mouth Handicap in Systemic Sclerosis Questionnaire (MHISS) in Turkish


Brief description of study

In this study, it is aimed to determine the validity, validity and reliability of the Mouth Handicap in Systemic Sclerosis (MHISS) scale in Turkish patients with Systemic Sclerosis; information will be obtained on application considerations. In addition, when we look at the literature, there is no Turkish scale evaluating oral involvement in patients with systemic sclerosis. In this context, we believe that our work will have a mission that will benefit new studies.

Detailed Study Description

Systemic Sclerosis is an autoimmune connective tissue disease with fibrosis. Although its etiology and pathogenesis have not been clearly defined, it has a chronic course. Systemic sclerosis is estimated to affect approximately 300,000 people in the United States. Most commonly, it affects adults and women.

Narrowing of the mouth opening and mouth pain are the two most important causes reported by adults with systemic sclerosis. In patients with systemic sclerosis, orofacial findings such as microstomy or reduced mouth opening are frequently seen. Microstomy is defined as the distance between the incisors is less than 40 millimeters. In severe microstomy, this distance is less than 30 millimeters. It is approximately 33 millimeters in adults with systemic sclerosis. Microstomy in systemic sclerosis mainly results from submucosal collagen deposits that contribute to fibrosis in the perioral tissue. Microstomy is seen in 43% to 80% of adults with systemic sclerosis.

When the current literature is examined, Bongi et al. evaluated the effectiveness of face-specific programs, which are applied together with general rehabilitation programs in patients with systemic sclerosis; they demonstrated that these techniques improve disability, health-related quality of life (HRQoL), and facial functionality.

A Turkish validity and reliability study based on patient reporting evaluating oral health has not been performed. When the literature was examined, outh Mouth Handicap in Systemic Sclerosis (MHISS) Scale "was found to be an objective method for assessing oral involvement in the MSS.

In 2007, the Mouth Handicap in Systemic Sclerosis (MHISS) Scale, which was published in English, was translated into Italian in 2012 and Dutch in 2013 and cultural adaptation was performed. No Turkish version was found in the literature.

The aim of this study was to investigate the validity, validity and reliability of the Turkish version of the Mouth Handicap in Systemic Sclerosis (MHISS) Scale in the evaluation of oral health of patients with Systemic Sclerosis. At the end of the study, the validity, reliability study will be conducted and the Turkish population will be translated into Turkish by using the Mouth Handicap in Systemic Sclerosis (MHISS) Scale, which allows assessment based on patient notification.

Clinical Study Identifier: NCT04273386

Find a site near you

Start Over

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


Volunteer Sign-up

Sign up for our FREE service to receive email notifications when clinical trials are posted in the medical category of interest to you.