Inventory of Radiological and Vestibular Function in Cochlear Implant Candidates

  • End date
    Dec 30, 2023
  • participants needed
  • sponsor
    Jessa Hospital
Updated on 19 April 2022
cochlear implant
hearing impairment


In 2014 radiological lesions at one or more semicircular canals (SCC) were described using CT & MR imaging in subjects presenting advanced hearing and vestibular deterioration caused by the p.P51S mutation in COCH. Similar lesions were also described in other non-genetic advanced hearing and vestibular deterioration as well. With this prospective observational study it is the purpose to inventory imaging results of candidates for cochlear implantation which are routinely performed during the preoperative work up, since these patient present severe hearing impairment at both ears. A considerable part of them might present vestibular deterioration as well. It is the purpose to detect possible presence of these SCC lesions on CT and MR in this population and the prevalence of these lesions compared to DFNA9 patients.

Condition Hearing Loss, Sensorineural, Bilateral Vestibular Deficiency, DFNA9, Radiology
Treatment video nystagmography
Clinical Study IdentifierNCT04066270
SponsorJessa Hospital
Last Modified on19 April 2022


Yes No Not Sure

Inclusion Criteria

must be eligible for cochlear implantation
must be 18 years of age or older

Exclusion Criteria

<18 years of age
not eligible to undergo vestibular tests, especially videonystagmography
contra-indication for MR or CT
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