Last updated on February 2020

Adherence of a 1.600 mg Single Tablet 5-ASA Treatment of Ulcerative Colitis

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Ulcerative Colitis | Ulcerative Colitis (Pediatric)
  • Age: Between 18 - 60 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Signed informed consent
  • Age between and including 18 and 60
  • Diagnosed with UC according to the Copenhagen Diagnostic Criteria
  • Length of disease of max. 10 years
  • Stable remission on 5-ASA (defined as partial Mayo score 1) for at least 2 months without need for oral corticosteroids before inclusion.
  • Endoscopic remission defined as Mayo Clinic Endoscopic Score < 2
  • Have had a relapse within the last 2 years
  • Defined as the need of escalation of treatment or change medical treatment.

Exclusion Criteria:

  • Evidence of infectious diarrhoea (i.e. pathogenic viruses, bacteria or Clostridium difficile toxin in stool culture) within the last month
  • On immunomodulators, including methotrexate
  • On any biological therapy
  • Any previous abdominal surgery related to UC
  • Any chronic infections (e.g. HBV, HCV, HIV)
  • Any severe concomitant cardiovascular, autoimmune, hematologic, hepatic, renal, endocrine, oncologic or psychiatric disorder, which in the opinion of the investigator might have an influence on the patient's compliance or the interpretation of the results
  • Well-founded doubt about the patient's cooperation, e.g., because of addiction to alcohol or drugs in the opinion of the investigators.
  • Participation in another clinical trial within the last 30 days, or simultaneous participation in another clinical trial.
  • Any previous documented allergic reaction to tested the medical drugs

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

Volunteer Sign-up

Sign up for our FREE service to receive email notifications when clinical trials are posted in the medical category of interest to you.