visuALL Field Analyzer (vFA) Compared to Standard Automatic Perimetry

  • days left to enroll
  • participants needed
  • sponsor
    Wills Eye
Updated on 9 July 2021
brimonidine tartrate ophthalmic solution
intraocular pressure
eye disease
optic neuropathy


To determine age-adjusted reference values of the visuALL Field Analyzer (vFA), to assess the repeatability for each parameter and correlate them with a Standard Automatic Perimetry (SAP) parameters.


Standard Automatic Perimetry (SAP) is the gold standard test for the evaluation of different diseases of the visual pathway like glaucoma. Its main goal is to measure the differential light sensitivity at several locations of the central and peripheral field of vision. Nevertheless, the accuracy of the current device is limited by several factors like the inherent inconsistency of the psychophysical test, stressful examinations and frequency of testing among others.

Several devices have been developed since the advent of the Octopus Perimeter3-5 and the Humphrey Field Analyzer (HFA), in an effort to improve early detection of glaucoma.

The main goal of this study is to evaluate the repeatability of a novel psychophysical platform that takes advantage of a Head Mounted Device (HMD) with eye tracking capabilities. Other objectives of this study include the development of an initial reference database and the evaluation of its correlation with HFA parameters.

Condition Pigmentary glaucoma, Open Angle Glaucoma
Treatment Standard Automatic Perimetry Humphrey Field Analyzer, visuALL Field Analyzer
Clinical Study IdentifierNCT03804684
SponsorWills Eye
Last Modified on9 July 2021


Yes No Not Sure

Inclusion Criteria

age 21 to 80 years
Healthy subjects with no eye diseases, normal appearing optic nerve and retina, intraocular pressure less than 19 millimeters mercury and normal standard automatic perimetry (SAP)
mild glaucoma subjects with less than -6 mean deviation
moderate glaucoma subjects with -6 to -12 mean deviation

Exclusion Criteria

spherical refraction outside 3.0 diopters and cylinder correction outside 2.0 diopters
Unreliable SAP (false positives, fixation losses and false negatives greater than 25% and/or observable testing artifacts)
Unreliable visuALL Field Analyzer (vFA) (greater than 25% false positive, excessive fixation losses)
SAP abnormality with pattern loss consistent with neurologic and/or other ocular diseases than glaucoma
Intraocular surgery in study eye (except non-complicated cataract or refractive surgery performed more than 6 months before enrollment and without posterior capsule opacification)
History of systemic condition known to affect visual function
History of medication known to affect visual function
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