Percutaneous Endoscopic Decompression for Lumbar Canal Stenosis

  • STATUS
    Recruiting
  • End date
    Dec 31, 2023
  • participants needed
    600
  • sponsor
    Peking University Third Hospital
Updated on 26 February 2022
anesthesia
ct scan
local anesthetic
local anesthesia
conservative management
local anesthetics
spinal decompression

Summary

Lumbar spinal stenosis (LSS) is the most common spinal degenerative disease. For conservative treatment failure, open lumbar decompression and fusion surgery is the main surgical treatment. After decades of development, open lumbar decompression and fusion surgery has been the standard treatment. However, there are still people and conditions that cannot be covered, such as elderly people who intolerable surgery, severe osteoporosis, and re-stenosis at adjacent segments after fusion. Percutaneous spinal endoscopic lumbar spinal decompression technique could be performed under local anesthesia, soft tissue damage is minimized, and effective spinal decompression can be achieved. There are still some controversial points of LSS decompression under percutaneous endoscope surgery, such as the range of decompression, choice of approach, postoperative spinal stability, learning curve, surgical safety, long-term effects of endoscopic treatment of restenosis at adjacent segments after fusion surgery. The purpose of this study was to solve these controversial points. A multi-center, prospective registration study based on the real world is planned. The total sample size is about 600 cases (300 cases in endoscopic surgery group, 300 cases in open decompression and fusion group). The mid- to long-term clinical efficacy and safety were evaluated.

Details
Condition Lumbar Spinal Stenosis, Surgery
Treatment Two different treatment
Clinical Study IdentifierNCT04254757
SponsorPeking University Third Hospital
Last Modified on26 February 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Patients with symptomatic lumbar canal stenosis(including central canal, lateral recess, foraminal and extraforaminal) despite more than 6 weeks of conservative treatment; Pathology was confirmed by both computed tomography and magnetic resonance imaging The operative level2

Exclusion Criteria

Segmental instability Simple disc herniation Coexisting pathological conditions, such as tumor and infection
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