A Study of Low and Standard-dose Ticagrelor After Intervention for ACS Patients

  • STATUS
    Recruiting
  • End date
    Dec 31, 2022
  • participants needed
    2120
  • sponsor
    Shanghai Tong Ren Hospital
Updated on 20 June 2021
Investigator
Lei Hou, Doctor
Primary Contact
The third people's hospital (6.7 mi away) Contact
+7 other location
aspirin
ticagrelor
percutaneous coronary intervention
acute coronary syndrome

Summary

This study is to evaluate the safety and efficacy of 60mg ticagrelor plus 100mg Aspirin to prevent major adverse cardiovascular and cerebrovascular events in one years after drug-eluting stents implantation for Chinese ACS patients compared with 90mg ticagrelor plus 100mg Aspirin

Details
Condition Acute Coronary Syndrome, Ischemic Heart Disease, Coronary Stent Implantation, Cardiac Ischemia, Myocardial Ischemia, acute coronary syndromes
Treatment Ticagrelor 60mg, Ticagrelor 90mg
Clinical Study IdentifierNCT04255602
SponsorShanghai Tong Ren Hospital
Last Modified on20 June 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Subject must be at least 18 years of age
Patients should have undergone successful percutaneous coronary intervention with drug-eluting stent for acute coronary syndrome
Subject understand the study requirements and the treatment procedures and provided informed consent before the procedure

Exclusion Criteria

Female of childbearing potential, unless a recent pregnancy test is negative, who possibly plan to become pregnant any time after enrollment into this study
Active bleeding
Known hypersensitivity or contraindication to study medications
Non-cardiac co-morbid conditions are present with life expectancy <2 year or that may result in protocol non-compliance (per site investigator's medical judgment)
Subjects with Cerebral hemorrhage history
Subjects with stroke history in half a year
subjects with malignant tumor
subjects with whom oral anticoagulants are needed
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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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