Effect of Ultrasound-guided Corticosteroid Injection Versus Palpation-guided Injection for de Quervain's Disease

  • STATUS
    Recruiting
  • End date
    Dec 31, 2024
  • participants needed
    70
  • sponsor
    Shin Kong Wu Ho-Su Memorial Hospital
Updated on 25 March 2022

Summary

The purposes of this study are to compare the effectiveness and side effects of US-guided and palpation-guided corticosteroid injections for de Quervain's disease.

Description

De Quervain's disease is a common clinical disorder, characterized by pain at radial side of the wrist. It often interferes wrist and thumb movement, and may affect activity of daily life. It is caused by overuse and impaired gliding of the abductor pollicis longus (APL) and extensor policis brevis (EPB) tendons at the styloid process of the radius. It is associated with postpartum baby care, or jobs or hobbies that involve repetitive hand and wrist motions. The most effective treatment is corticosteroid injection into the tendon sheath of the conjoined tendons of APL and EPB. Over the past few years because of advancement of sonography in the musculoskeletal system, ultrasound (US)-guided intra-sheath injection has become popular, and it has been proved to improve the accuracy of placement of needle tip in the tendon sheath, however, studies comparing the effect and side effects of US-guided corticosteroid injection with palpation-guided injection for de Quervain's disease have never been reported before. The purposes of this study are to compare the effectiveness and side effects of US-guided and palpation-guided corticosteroid injections for de Quervain's disease.

The investigators plan to recruit 70 patients with de Quervain's disease, half of them will be randomly assigned into US-guided injection group, and the other half into the palpation-guided injection group. Each subject will receive one shot of injection and each subject will expect to fill in the evaluation form at baseline, and at 1 week, 3 months, and 6 months after the injection. Statistics will be performed after completing the patients' treatment and evaluations.

Details
Condition De Quervain Disease
Treatment US-guided injection, palpation-guided injection
Clinical Study IdentifierNCT04260984
SponsorShin Kong Wu Ho-Su Memorial Hospital
Last Modified on25 March 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Pain and tenderness at the radial side of the wrist
Positive Finkelstein sign, or pain on resistive maximal isometric contraction of extension and/or abduction of the affected thumb
pain intensity on a 10-point visual analog scale (VAS) for pain to ≧ 3 on active thumb abduction or extension
Patient agrees to receive either palpation-guided or US-guided local corticosteroid injection
Age ≧ 20 years old

Exclusion Criteria

Presence of an absolute contraindication for corticosteroids or local anesthetics injection
During pregnancy
Severe systemic diseases with poor control
Prior treatment with corticosteroid injection and/or surgery at the same anatomical location in the last 6 months
Being unable to fill-in the follow-up forms
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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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