Carpal Tunnel Syndrome and Amyloidosis (AMICAR)

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  • sponsor
    Corporacion Parc Tauli
Updated on 25 February 2022
amyloid deposition
carpal tunnel release


Carpal tunnel syndrome has been suggested to be an early sign of amyloidosi. The investigators will evaluate tissue samples obtained from patients undergoing carpal tunnel release surgery for amyloid.


Carpal tunnel syndrome (CTS) can be caused by the deposition and accumulation of misfolded proteins called amyloid and is often an early manifestation of systemic amyloidosis.

Patients with cardiac amyloidosis often have carpal tunnel syndrome that precedes cardiac manifestations by several years, and many patients will have undergone surgery for idiopathic carpal tunnel syndrome since the protein also deposits in the transversal carpal ligament of the hand.

The investigators sought to identify the prevalence and type of amyloid deposits in patients undergoing carpal tunnel surgery and evaluate for cardiac involvement

Condition Amyloidosis, Carpal Tunnel Syndrome
Treatment Carpal tunnel syndrome surgery
Clinical Study IdentifierNCT04245098
SponsorCorporacion Parc Tauli
Last Modified on25 February 2022


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Inclusion Criteria

Patients undergoing carpal tunnel syndrome surgery

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