Verification of Predictive Biomarkers for Pancreatic Cancer Treatment Using Multicenter Liquid Biopsy

  • End date
    Dec 31, 2025
  • participants needed
  • sponsor
    National Cancer Center, Korea
Updated on 25 February 2022


This study is for verification of predictive biomarkers for pancreatic cancer treatment using multi-center liquid biopsy.


Clinical applicability of KRAS mutations using circulating-tumor DNA in pancreatic cancer patients.

  • Quantification and monitoring of KRAS mutations Using droplet digital PCR in ctDNA extracted from collected patient samples.
  • Correlation analysis of KRAS mutation results with clinical data.

Discovery of biomarkers for predicting pancreatic cancer prognosis through ctDNA panel.

  • Gene panel composition for pancreatic cancer therapeutic target determination and monitoring.
  • A panel was performed using gDNA and ctDNA of tumor tissue collected from pancreatic cancer patients.
  • Comparative analysis of panel results and quantitative KRAS mutations and evaluation of clinical applicability.

Condition Pancreas Adenocarcinoma
Clinical Study IdentifierNCT04241367
SponsorNational Cancer Center, Korea
Last Modified on25 February 2022


Yes No Not Sure

Inclusion Criteria

Patients with pathologically confirmed pancreatic adenocarcinoma

Exclusion Criteria

Patients disagree with the study
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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