Pectoralis and Serratus Muscle Blocks
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- STATUS
- Recruiting
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- End date
- Dec 26, 2022
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- participants needed
- 192
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- sponsor
- The Cleveland Clinic
Summary
The overall research plan is PECS/SAP blocks with liposomal bupivacaine improve the Overall Benefit Analgesia Score averaged over the postoperative days 1, 2, and 3. A 2-point reduction in OBAS will be considered the minimal clinically important benefit.
Description
The primary aim is to determine whether a PECS/SAP block, using a mixture of bupivacaine and liposomal bupivacaine, provides superior recovery compared to routine parenteral and enteral analgesia in patients recovering from MICS. The primary outcome will be the simple multi-dimensional quality assessment, Overall Benefit Analgesia Score (OBAS score).53 Our secondary aims are to: 1) compare cumulative postoperative opioid consumption (pain medications administered over one-day periods quantified as morphine equivalents and provided by the EMR for the day of surgery and postoperative days 1, 2, and 3; 2) evaluate respiratory mechanics (forced expiratory volume in first minute (FEV1), forced vital capacity (FVC) and peak flow) after extubation on the postoperative days 1, 2 and 3 while patients remain hospitalized; and, (3) evaluate the Quality-of-Recovery-15 score on the postoperative days 1, 2 and 3.
Details
| Condition | Post Operative Pain Control |
|---|---|
| Treatment | Placebo, Exparel 266 MG Per 20 ML Injection |
| Clinical Study Identifier | NCT03743194 |
| Sponsor | The Cleveland Clinic |
| Last Modified on | 26 March 2022 |
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