Evolution and Treatments of Chronic Inflammatory Systemic Diseases (MISTIC)

  • End date
    Dec 23, 2029
  • participants needed
  • sponsor
    Centre Hospitalier Universitaire de Besancon
Updated on 25 February 2022
ulcerative colitis
inflammatory bowel disease
inflammatory disease
crohn's disease
rheumatic diseases
rheumatoid arthritis
psoriatic arthritis
ankylosing spondylitis
indeterminate colitis


Patients with chronic inflammatory diseases (CID) followed in gastroenterology and rheumatology have physiopathological, epidemiological and therapeutic focal points. The pathologies concerned are inflammatory bowel diseases (IBD - Crohn's disease [MC] and ulcerative colitis [RCH]), and chronic inflammatory rheumatic diseases (rheumatoid arthritis [RA] and spondyloarthritis [SpA] including psoriatic arthritis [PsA]). Presenting one of these diseases is associated with a higher risk of having a second inflammatory pathology, whether the latter is ophthalmological, dermatological, rheumatological or gastroenterological. An association of extra-articular manifestations is observed in 10 to 30% of patients with SpA, and an association of extra-intestinal manifestations is observed in approximately 30% of patients with IBD. No common database for chronic systemic inflammatory diseases currently exists in France.

Condition Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease, Arthritis, Rheumatoid, Spondyloarthritis, Psoriatic Arthritis
Clinical Study IdentifierNCT04191395
SponsorCentre Hospitalier Universitaire de Besancon
Last Modified on25 February 2022


Yes No Not Sure

Inclusion Criteria

Patients treated for IBD (MC, UC or indeterminate colitis) in the gastroenterology department of Besanon University Hospital
Subject meeting the clinical, morphological and histological diagnostic criteria for MC, UC or indeterminate colitis or
Patients treated for chronic inflammatory rheumatism (RA, SpA, PsA) in the rheumatology department of the University Hospital of Besanon Subject meeting the ACR 2010 classification criteria of RA or modified New York criteria of Ankylosing spondylitis or ASAS criteria of axial or peripheral SpA or CASPAR criteria of PsA

Exclusion Criteria

Opposition of the patient
Patients in emergency situation, persons deprived of their liberty, protected minors or adults
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