The purpose of this study is to test whether the study drug prexasertib is a safe and
effective treatment for people with DSRCT or RMS when given in combination with the standard
drugs irinotecan and temozolomide. The study will test different doses of prexasertib in
combination with irinotecan and temozolomide to find the highest dose of prexasertib that
causes few or mild side effects in participants.
If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.
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