Vitamin D3 in Sensory Recovery After Digital NERVe Suture (D3NERV). (D3NERV)

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    University Hospital, Caen
Updated on 7 February 2023


Digital nerve injuries are frequent in a FESUM center (Federation Europenne des Services d'Urgences Mains), and they need to be repaired in order to reduce the risk of hypoesthesia and to prevent painful neuroma. Several animal studies have shown that Cholecalciferol improves axonal nerve regeneration and myelination. No study has ever been done on human subjects to evaluate the nerve regeneration after Cholecalciferol supplementation.

Our hypothesis is that Cholecalciferol supplementation could improve axonal nerve regeneration and myelination after traumatic digital nerve injuries treated by microsurgical sutures and reduce the risk of hypoesthesia and neuroma.

Condition Digital Nerve Injury
Treatment Cholecalciferol, placebos
Clinical Study IdentifierNCT04115982
SponsorUniversity Hospital, Caen
Last Modified on7 February 2023

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