EXPLORER PET/CT in Healthy Volunteers

  • End date
    Jul 19, 2023
  • participants needed
  • sponsor
    University of California, Davis
Updated on 14 May 2022
Accepts healthy volunteers


The objective of this pilot study is to collect preliminary data using total body scans on a new, first of its kind, FDA 510k-cleared positron emission tomography/computed tomography (PET/CT) scanner, called EXPLORER.

Condition Healthy
Clinical Study IdentifierNCT04110743
SponsorUniversity of California, Davis
Last Modified on14 May 2022


Yes No Not Sure

Inclusion Criteria

Men and women, 18 years of age or older
Willing and able to fast for at least 6 hours before and for the duration of the scan
Willing and able to lay motionless in a supine position for 60 and 20 minutes at separate timepoints
Willing and able to give informed consent

Exclusion Criteria

No Primary Care Physician
Body weight >240 kg
Allergy to iodine contrast (only for subjects enrolled in Arm 3)
Creatinine levels > 1.5 mg/dL or estimated glomerular filtration rate (eGFR) < 60 ml/minute (only for subjects enrolled in Arm 3)
Recent (1 month) contrast enhanced CT
Any known concomitant acute infection (including upper respiratory infection, genitourinary infections, etc
History of metastatic or newly (last 5 years) diagnosed locally invasive cancer
Chemotherapy in the last 5 years
Radiation therapy in the last 3 years
Major surgery within the last 6 months
Pregnancy or breast-feeding
Fasting blood glucose level > 160 mg/dL before administration of FDG
The standard MRI contraindications apply, including but not limited to
Having a pacemaker or other implanted electronic device. Metal foreign bodies, aneurysm
clips, heart valve prosthesis, vascular stents, cochlear implants, embolization coils
gunshot wounds with retained bullet fragments, penile implant, IUCD
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How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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