A Study to Evaluate the Safety and Efficacy of PF-06650833 PF-06700841 and PF 06826647 in Adults With Hidradenitis Suppurativa

  • STATUS
    Recruiting
  • End date
    Dec 27, 2021
  • participants needed
    192
  • sponsor
    Pfizer
Updated on 25 July 2021
hidradenitis

Summary

This is a study with 3 kinase inhibitors (PF 06650833, PF 06700841 and PF 06826647) in participants with moderate to severe HS. The study will have a maximum duration of approximately 26 weeks. This includes an up to 6-week Screening Period, a 16 week Dosing Period and a 4 week Follow up Period.

Details
Condition Hidradenitis Suppurativa, Acne Inversa
Treatment Placebo, PF-06700841, PF-06650833, PF-06826647
Clinical Study IdentifierNCT04092452
SponsorPfizer
Last Modified on25 July 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

male or female participants, between 18-75, with a diagnosis of moderate to severe Hidradenitis Suppurativa

Exclusion Criteria

History of human immunodeficiency virus (HIV) or positive HIV serology at screening
Infected with hepatitis B or hepatitis C viruses
Have evidence of active or latent or inadequately treated infection with Mycobacterium tuberculosis (TB)
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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