Last updated on July 2020

A Phase 2, Open-Label, Randomized, Multicenter Study to Evaluate the Efficacy and Safety of Pemigatinib Plus Pembrolizumab Versus Pemigatinib Alone Versus Standard of Care as First-Line Treatment for Metastatic or Unresectable Urothelial Carcinoma in Cisplatin-Ineligible Participants Whose Tumors Express FGFR3 Mutation or Rearrangement


Brief description of study

The purpose of this study is to evaluate the safety and efficacy of pemigatinib plus pembrolizumab or pemigatinib alone versus the standard of care for participants with metastatic or unresectable urothelial carcinoma who are not eligible to receive cisplatin, are harboring FGFR3 mutation or rearrangement, and who have not received prior treatment.

 

Clinical Study Identifier: TX233310

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Osaka International Cancer Institute

Located in: Osaka-Shi, Osaka Japan
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Chiba Cancer Center

Located in: Chiba, Japan
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Charleston Hematology Oncology Associates

Located in: Charleston, South Carolina United States
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The Center For Cancer And Blood Disorders

Located in: Fort Worth, Texas United States
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Christiana Care Helen F. Graham Cancer Center

Located in: Newark, Delaware United States
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ONC Consultants Pharmacy 2

Located in: Houston, Texas United States
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Summit Medical Group

Located in: Florham Park, New Jersey United States
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Hospital Universitario De La Paz

Located in: Madrid, Madrid Spain
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Hospital Puerta De Hierro

Located in: Majadahonda, Spain
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Toranomon Hospital

Located in: Minato-Ku, Minato-Ku Japan
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National Cancer Center Hospital

Located in: Tokyo, Tokyo Japan
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NHO Shikoku Cancer Center

Located in: Matsuyama, Matsuyama Japan
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Oregon Health Science University

Located in: Portland, Oregon United States
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Southern Illinois University School of Medicine

Located in: Springfield, Illinois United States
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Hospital Clinico San Carlos

Located in: Madrid, Spain
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Hospital Clinic I Provincial

Located in: Barcelona, Barcelona Spain
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Kagawa University Hospital

Located in: Kita-Gun, Kita-Gun Japan
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St. Marianna University School of Medicine HP

Located in: Kawasaki-Shi, Kawasaki-Shi Japan
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Keio University Hospital

Located in: Shinjuku-Ku, Shinjuku Japan
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HUH Cancer Center

Located in: Helsinki, Helsinki Finland
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Universitaire Ziekenhuizen Leuven

Located in: Leuven, Leuven Belgium
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Tohoku University Hospital

Located in: Miyagi-Ken, Miyagi Japan
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Hospital Universitario HM Sanchinarro

Located in: Madrid, Madrid Spain
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Osaka University Hospital

Located in: Suita-Shi, Suita-Shi Japan
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Hakodate Goryokaku Hospital

Located in: Hokkaido, Hokkaido Japan
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Sapporo Medical University Hospital

Located in: Hokkaido, Hokkaido Japan
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NARA Medical University Hospital

Located in: Kashihara-Shi, Kashihara-Shi Japan
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SMHC Cancer Blood Disorders

Located in: Biddeford, Maine United States
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Marin Cancer Center

Located in: Greenbrae, California United States
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Mount Sinai School of Medicine

Located in: New York, New York United States
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Toyama University Hospital

Located in: Toyama, Toyama Japan
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Grand Hopital De Charleroi

Located in: Charleroi, Charleroi Belgium
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Hospital Universitario Virgen Del Rocio

Located in: Sevilla, Sevilla SPAIN
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IRRCS Instituto Clinico Humanitas

Located in: Rozzano, Rozzano Italy
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Groupe Hospitalier Pellegrin Tripode

Located in: Bordeux, Bordeux France
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Turku University Hospital, SCT Unit

Located in: Turku, Turku Finland
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ICO Girona

Located in: Girona, Girona Spain
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CHU Nimes

Located in: Nimes, Nimes France
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Vanderbilt-Ingram Cancer Center

Located in: Nashville, Tennessee United States
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Chiba University Hospital

Located in: Chiba, Chiba Japan
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Fonk Onkologian Klinikka

Located in: Tampere, Tampere Finland
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Recruitment Status: Open


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