Somatostatin Receptor Imaging in Acute Myocarditis and Cardiac Sarcoidosis

  • End date
    Dec 12, 2024
  • participants needed
  • sponsor
    Vastra Gotaland Region
Updated on 12 May 2022


This prospective imaging study investigates the diagnostic ability of Gallium-68 DOTA-TOC (68Ga-DOTA-TOC) positron emission tomography/computed tomography (PET/CT) in the clinical work-up of patients with 1) clinically suspected acute myocarditis (n=30-40) and 2) clinically suspected cardiac sarcoidosis (n=30-40) using clinical diagnostic criteria as well as endomyocardial biopsy as reference. Furthermore, 68Ga-DOTA-TOC PET/CT findings will be compared with results from contrast-enhanced magnetic resonance imaging (MRI) and in case of cardiac sarcoidosis even Fluorine-18 fluorodeoxyglucose (18F-FDG) PET/CT, which are both performed as part of the clinical routine work-up.

Condition Acute Myocarditis, Cardiac Sarcoidosis
Treatment Blood sample, 68Ga-DOTA-TOC PET/CT
Clinical Study IdentifierNCT04206163
SponsorVastra Gotaland Region
Last Modified on12 May 2022


Yes No Not Sure

Inclusion Criteria

Willingness to participate in the study
Provision of written informed consent
All patients between the age of 18 and 85 of both genders
Newly clinically suspected acute myocarditis or newly clinically suspected cardiac sarcoidosis with or without known extra-cardiac sarcoid

Exclusion Criteria

Pregnancy or lactation
Severe obesity (limited by the scanner)
Other known significant cardiac disease, including previous myocarditis
Known tumour disease, especially (neuro)endocrine tumours
Terminal disease(s), advanced psychiatric disease and/or significant dementia
Recent or current immunosuppressive treatment
Recent or current somatostatin analogue (octreotide) therapy
Known relative/absolute contraindications for contrast-enhanced MRI and/or PET/CT imaging
Known contraindications for endomyocardial biopsy
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact


Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider


Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 



Reply by • Private

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note