Mite Allergy Trial In Children (MATIC)

    Not Recruiting
  • End date
    Apr 9, 2023
  • participants needed
  • sponsor
    ALK-Abelló A/S
Updated on 2 June 2022


A research study of how house dust mite tablets work compared to placebo in children aged between 5 and 11 years and who have allergy to house dust mites (MATIC)


The trial aims to demonstrate efficacy of the House Dust Mite SLIT-tablet compared to placebo in children (5-11 years of age) with House Dust Mite allergic rhinitis based on the total combined rhinitis symptoms and medication score during the last 8 weeks of treatment.

In addition, the trial will evaluate safety and tolerability of the treatment, and assess whether treatment has an impact on asthma symptoms and medication use, immunological parameters, and rhinoconjunctivitis quality of life (QoL).

The trial is a randomised, parallel-group, double-blind, placebo-controlled multi-national phase III trial conducted in Europe and North America. The treatment period will be approximately 1 year.

Condition Allergic Rhinitis Due to Dermatophagoides Farinae, Allergic Rhinitis Due to Dermatophagoides Pteronyssinus, Allergic Rhinitis Due to House Dust Mite
Treatment Placebo, Sublingual allergy immunotherapy tablet
Clinical Study IdentifierNCT04145219
SponsorALK-Abelló A/S
Last Modified on2 June 2022

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