The Effectiveness of Patient-tailored Treatment in Patients With (Sub)Acute Neck Pain

  • STATUS
    Recruiting
  • End date
    Oct 2, 2025
  • participants needed
    150
  • sponsor
    University Ghent
Updated on 20 February 2022
cancer
manual therapy
arm pain
neck exercises

Summary

The purpose of this study is to assess the safety, tolerability, and efficacy of BMS-986158 alone and in combination with either Ruxolitinib or Fedratinib in participants with Dynamic International Prognostic Scoring System (DIPSS)-intermediate or high risk blood cancer. Part 1 consists of BMS-986158 in combination with either Ruxolitinib or Fedratinib and Part 2 consists of BMS-986158 in combination with either Ruxolitinib or Fedratinib and BMS-986158 alone.

Details
Condition Neck Pain, Acute Pain, Rehabilitation, Physical Therapy Modalities
Treatment Education, patient-tailored therapy, Non-patient tailored therapy: generalized exercise program
Clinical Study IdentifierNCT04182035
SponsorUniversity Ghent
Last Modified on20 February 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Non-specific neck pain, pain located in the cervico-thoracic and posterior shoulder region; without dominant arm pain
NDI scores score 10 % (more than no disability) and 68 % (less than complete disability)
(Sub)acute complaints: <3 months
Recurrent complaints but no neck pain episode the previous 3 months
Mean pain intensity scores: NRS > 3/10

Exclusion Criteria

Structural pathology, confirmed by imaging (disk herniation, nerve root compression, radiculopathy, severe rheumatoid diseases, fractures, traumatic alterations) Shoulder pathology, vestibular pathology
Risk stratification: Startback tool for neck pain: high risk group
BMI > 30 kg/m
Other cardiovascular/metabolic/systemic/ neurological diseases, fibromyalgia or chronic fatigue syndrome
Psychiatric illnesses, history of depression, serious catastrophizing thoughts and/or low treatment expectations.[52]
Chronic complaints (>3 months) or traumatic onset of the complaints
Probable or definite neuropathic pain (according to the classification of Finnerup et al.)
History of surgery in the head/neck or shoulder region
Hypermobile patients
Pregnancy or given birth in the preceding year
History of recurrent/chronic low back pain
Primary headache
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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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