Intravenous Acetaminophen and Morphine Versus Intravenous Morphine Alone for Acute Pain in the Emergency Department (ADAMOPA)
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- STATUS
- Recruiting
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- End date
- Jun 3, 2024
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- participants needed
- 572
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- sponsor
- Nantes University Hospital
Summary
In emergency medicine, acute pain is a common reason for consultation. It is recommended that patients in moderate to severe pain should receive a combination of intravenous acetaminophen and morphine. However, the data are sparse to support this strategy. Thus, the purpose of our research is to test non-inferiority of IV morphine alone versus IV acetaminophen and morphine in a multicenter, randomized, controlled double blind trial in ED patients with moderate to severe acute pain.
Description
This study is designed to assess whether IV morphine alone is non inferior to combination IV acetaminophen and morphine for the management of moderate to severe pain in the ED. Numeric rating scale pain score will be compared between those who receive morphine alone and who will receive acetaminophen and morphine at 15, 30, 45 and 60 min post first injection.
Details
| Condition | Pain Management |
|---|---|
| Treatment | placebo of acetaminophen IV, acetaminophen IV |
| Clinical Study Identifier | NCT04148495 |
| Sponsor | Nantes University Hospital |
| Last Modified on | 22 April 2022 |
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