Scalp Cooling in Gynecologic Cancer Patients

  • STATUS
    Not Recruiting
  • days left to enroll
    11
  • participants needed
    70
  • sponsor
    The University of Hong Kong
Updated on 5 March 2022
paclitaxel
cancer
ifosfamide

Summary

In gynecologic cancers, many common chemotherapy agents can lead to chemotherapy-induced alopecia. Currently scalp cooling is the most well studied preventive measure. However, its acceptability and its impact on patients' QOL in Asian population is unclear.

Description

Dynamic scalp cooling system prevents alopecia by inducing vasoconstriction leading to a reduction of scalp blood flow, thus reducing the delivery of cytotoxic drugs to the hair follicles and reducing follicular metabolic activities. One recent meta-analysis included 10 studies showed that the efficacy was 43% in general.

Details
Condition Gynecologic Cancer, Chemotherapy-Induced Change
Treatment Standard Treatment, Scalp cooling Paxman Orbis II system
Clinical Study IdentifierNCT04168242
SponsorThe University of Hong Kong
Last Modified on5 March 2022

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