In gynecologic cancers, many common chemotherapy agents can lead to chemotherapy-induced alopecia. Currently scalp cooling is the most well studied preventive measure. However, its acceptability and its impact on patients' QOL in Asian population is unclear.
Dynamic scalp cooling system prevents alopecia by inducing vasoconstriction leading to a reduction of scalp blood flow, thus reducing the delivery of cytotoxic drugs to the hair follicles and reducing follicular metabolic activities. One recent meta-analysis included 10 studies showed that the efficacy was 43% in general.
| Condition | Gynecologic Cancer, Chemotherapy-Induced Change |
|---|---|
| Treatment | Standard Treatment, Scalp cooling Paxman Orbis II system |
| Clinical Study Identifier | NCT04168242 |
| Sponsor | The University of Hong Kong |
| Last Modified on | 5 March 2022 |
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