Scalp Cooling in Gynecologic Cancer Patients

    Not Recruiting
  • participants needed
  • sponsor
    The University of Hong Kong
Updated on 6 July 2022


In gynecologic cancers, many common chemotherapy agents can lead to chemotherapy-induced alopecia. Currently scalp cooling is the most well studied preventive measure. However, its acceptability and its impact on patients' QOL in Asian population is unclear.


Dynamic scalp cooling system prevents alopecia by inducing vasoconstriction leading to a reduction of scalp blood flow, thus reducing the delivery of cytotoxic drugs to the hair follicles and reducing follicular metabolic activities. One recent meta-analysis included 10 studies showed that the efficacy was 43% in general.

Condition Gynecologic Cancer, Chemotherapy-Induced Change
Treatment Standard Treatment, Scalp cooling Paxman Orbis II system
Clinical Study IdentifierNCT04168242
SponsorThe University of Hong Kong
Last Modified on6 July 2022

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