Last updated on June 2018

In Vivo Endomicroscopic Description of Pulmonary Microcirculation in Systemic Sclerosis and Emphysema Patients


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Emphysema | Pulmonary Disease
  • Age: Between 18 - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Patients with scleroderma with diffuse interstitial pneumonia, indicating a bronchoscopy.
  • Patients with pulmonary emphysema indication for bronchoscopy.
  • Age greater than 18 years.
  • Having an affiliation to social security.
  • Signed informed consent.

Exclusion Criteria:

  • Severe chronic respiratory insufficiency against-indicating the completion of a bronchoscopy
  • Hypercapnia defined by a PaCO2 6 kPa
  • Disorders of hemostasis against-indicating performing a bronchoscopy
  • Anticoagulant therapy can not be interrupted time of completion of the examination
  • A history of pneumonectomy or contralateral exploration in a nonfunctional lung
  • Contraindication to the injection of fluorescein (including treatment with beta-blocker eye drops or po) or one of its excipients
  • History of an injection poorly tolerated fluorescein
  • A history of food allergy or drug known
  • Myocardial infarction <1 month
  • Unstable angina
  • Pregnant or lactating woman, premenopausal women without adequate contraception
  • Person under guardianship
  • Patient participating in another trial / participating in another trial within 4 weeks

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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