Prevalence and Spectrum of Cancer Susceptibility Among Patients With Advanced Colorectal Polyps

  • End date
    Jul 24, 2025
  • participants needed
  • sponsor
    University of Colorado, Denver
Updated on 24 May 2022
colorectal polyps


The study is being conducted to determine the prevalence and risk factors for germline cancer susceptibility genetic mutations among patients with advanced colorectal polyps.

Condition Colorectal Neoplasm
Treatment Multi-Cancer Cancer Panel
Clinical Study IdentifierNCT04160832
SponsorUniversity of Colorado, Denver
Last Modified on24 May 2022


Yes No Not Sure

Inclusion Criteria

Provision to sign and date the consent form
Stated willingness to comply with all study procedures and be available for the duration of the study
Be a male or female aged 18-89
Undergone colonoscopy
At least one advanced colorectal polyp, defined as having any of the following
Any polyp ≥ 1cm (adenoma or serrated polyp)
Any polyp with villous architecture
Any polyp with high-grade dysplasia
Sessile serrated polyps with any dysplasia
Traditional serrated adenoma

Exclusion Criteria

Known hereditary cancer syndrome
Personal history of inflammatory bowel disease
Personal history of colorectal cancer
Polyp histology or size unavailable or not documented
Clear my responses

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What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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