Pain Management Following Sinus Surgery

  • STATUS
    Recruiting
  • End date
    Dec 25, 2022
  • participants needed
    300
  • sponsor
    University of Nebraska
Updated on 18 February 2022
analgesia
postoperative pain
oxycodone
ibuprofen
narcotics
NSAID
anti-inflammatory agent
tylenol
sinus surgery
Accepts healthy volunteers

Summary

This Study evaluates the effect of adding Non-steroidal anti-inflammatories (NSAIDs) to the post-operative pain management of sinus surgery patients and wether or not this addition reduces or eliminates the need for narcotic pain medications.

Patients will be instructed to take an NSAID regimen after surgery and will be instructed to take narcotics only for breakthrough pain.

Description

National attention has been given to the concerning rise of opioid abuse in this country, with prescriptions for this medications more than quadrupaling in the last 17 years.

Little is known as to the appropriate use of opioid analgesics in the post-operative recovery of patients undergoing sinus surgery. Furthermore, most pain protocols include only Tylenol based opioid analgesics. No study has prospectively evaluated the volume of use of Tylenol based opioid analgesics and whether the addition of NSAIDS decreased the need for opioid analgesics.

This study will compare opioid use with and without the addition of NSAIDS following sinus surgery.

Post-operative opioid use is a great public health concern, relatively unstudied, and an area with an opportunity for potential intervention to significantly reduce risks, morbidity, and mortality to our postoperative patients by better formulating a postoperative pain management plan using evidence-based practices. Appropriate opioid prescribing practices can reduce the risk of addiction, drug overdose, death, and undertreated pain. By optimizing post-operative pain management protocols, the need for opioids following sinus surgery should be minimized.

Details
Condition Nasal Sinus; Inflammation, Opioid Abuse, Pain, Postoperative
Treatment Ibuprofen 600Mg Tablet, Standard Regimen | Tylenol
Clinical Study IdentifierNCT03822962
SponsorUniversity of Nebraska
Last Modified on18 February 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

All patients age 18-65 undergoing functional endoscopic sinus surgery +/-
nasal airway surgery (septoplasty and/or inferior turbinate reduction)

Exclusion Criteria

Not taking anti-coagulation medications including aspirin
Clinical Diagnosis of aspirin-exacerbated respiratory disease
Clinical Diagnosis of Cystic Fibrosis
Clinical Diagnosis of Primary Ciliary Dyskinesia
Inclusion of a Draf III frontal sinusotomy
Clinical Diagnosis of Liver/Kidney Failure
Clinical Diagnosis of Thrombocytopenia
Clinical Diagnosis of Poorly controlled hypertension
Clinical Diagnosis of Recent GI ulcers or gastritis
Clinical Diagnosis of Chronic pain as defined by a narcotic prescription with 6 months or involvement in a pain management program
Clinical Diagnosis of Primary Headache disorder
The use of nasal decongestants in the post-operative period
The use of nasal packing or absorbable biomaterials
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