Distribution, Pharmacokinetics and Extent of Sensory Blockade in ESP Blocks

  • participants needed
  • sponsor
    Milton S. Hershey Medical Center
Updated on 5 June 2023
Accepts healthy volunteers


The primary objectives of this study are to define the extent of dermatomal anesthesia and anatomical spread of injectate (as defined by MRI imaging) that is provided by an ESP block at the T5 level, using twenty milliliters of 0.5% ropivacaine.

The secondary objectives include: 1) the measurement of changes in hemodynamic parameters associated with the ESP block, 2) the duration of sensory effects provided by ropivacaine with or without epinephrine, 3) the venous plasma concentration of ropivacaine associated at various time intervals after completion of the ESP block.

Condition Distribution of Ropivacaine in Erector Spinae Plane Block
Treatment ropivacaine, Epinephrine
Clinical Study IdentifierNCT03476642
SponsorMilton S. Hershey Medical Center
Last Modified on5 June 2023

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