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Last updated on December 2019

A Study of Nivolumab in Combination With Ipilimumab in Participants With Advanced Hepatocellular Carcinoma

Brief description of study

The main purpose of this study is to compare the overall survival (OS) of nivolumab plus ipilimumab versus standard of care (SOC) (sorafenib or lenvatinib) in all randomized participants with advanced hepatocellular carcinoma (HCC) who have not received prior systemic therapy.

Clinical Study Identifier: NCT04039607

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Duarte, CA United States

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Orange, CA United States

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Palo Alto, CA United States

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Washington, WA United States

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Louisville, KY United States

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Baltimore, MD United States

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Detroit, MI United States

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Duluth, MN United States

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Minneapolis, MN United States

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New York, NY United States

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Rochester, NY United States

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Cleveland, OH United States

Toledo Clinic Cancer Center

Toledo, OH United States

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Lubbock, TX United States

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Salt Lake City, UT United States

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Charlottesville, VA United States

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Seattle, WA United States

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Madison, WI United States

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Caba, Argentina

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Pilar, Argentina

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Buenos Aires, Argentina

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Tucuman, Argentina

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Kogarah, Australia

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Liverpool, Australia

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Westmead, Australia

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Birtinya, Australia

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Herston, Australia

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Adelaide, Australia

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Clayton, Australia

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Melbourne, Australia

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Parkville, Australia

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Graz, Austria

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Innsbruck, Austria

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Klagenfurt, Austria

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St. Polten, Austria

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Wiener Neustadt, Austria

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Wien, Austria

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Brussels, Belgium

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Gent, Belgium

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Haine Saint Paul, Belgium

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Leuven, Belgium

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Liege, Belgium

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Salvador, Brazil

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Brasilia, Brazil

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Curitiba, Brazil

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Jau, Brazil

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Sao Paulo, Brazil

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Asa Sul, Brazil

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Pelotas, Brazil

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Rio de Janeiro, Brazil

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S?o Paulo, Brazil

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Edmonton, AB Canada

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Montreal, Canada

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La Serena, Chile

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Vina del Mar, Chile

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Santiago, Chile

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Hefei, China

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Beijing, China

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Fuzhou, China

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Guangzhou, China

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Harbin, China

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Changsha, China

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Nanjing, China

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Nanchang, China

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Changchun, China

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Dalian, China

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Shenyang, China

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Xi'an, China

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Xian, China

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Qingdao, China

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Hangzhou, China

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Chongqing, China

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Jilin, China

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Shanghai, China

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Amiens, France

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CAen, France

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Clichy, France

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Dijon, France

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La Tronche, France

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Lyon, France

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Montpellier, France

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Nice, France

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Pessac, France

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Poitiers, France

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Rennes, France

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Toulouse Cedex 9, France

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Vandoeuvre les Nancy, France

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Villejuif, France

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Frankfurt, Germany

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Berlin, Germany

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Essen, Germany

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Freiburg I. Breisgau, Germany

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Hamburg, Germany

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Hannover, Germany

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Koeln, Germany

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Leipzig, Germany

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Magdeburg, Germany

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Mainz, Germany

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Mannheim, Germany

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Munich, Germany

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Wuerzburg, Germany

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Hong Kong, Hong Kong

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Bergamo, Italy

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Candiolo, Italy

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Meldola, Italy

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Milano, Italy

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Novara, Italy

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Parma, Italy

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Roma, Italy

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Rome, Italy

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Rozzano MI, Italy

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Siena, Italy

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Vicenza, Italy

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Kashiwa-shi, Japan

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Fukuoka, Japan

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Sapporo, Japan

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Kanazawa, Japan

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Kyoto-shi, Japan

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Kanagawa, Japan

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Osaka, Japan

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Tokyo, Japan

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Busan, Korea, Republic of

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Gyeonggi-do, Korea, Republic of

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Gyeongsangnam-do, Korea, Republic of

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Jongno-gu, Korea, Republic of

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Seongnam-si, Korea, Republic of

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Seoul, Korea, Republic of

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Auckland, New Zealand

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Gdansk, Poland

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Otwock, Poland

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Warszawa, Poland

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San Juan, Puerto Rico

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Bucharest, Romania

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Cluj Napoca, Romania

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Craiova, Romania

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Timisoara, Romania

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Arkhangelsk, Russian Federation

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Barnaul, Russian Federation

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Chelyabinsk, Russian Federation

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Krasnoyarsk, Russian Federation

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Moscow, Russian Federation

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Pyatigorsk, Russian Federation

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Saint-Petersburg, Russian Federation

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Sochi, Russian Federation

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St.petersburg, Russian Federation

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Singapore, Singapore

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Barcelona, Spain

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Cordoba, Spain

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Madrid, Spain

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Murcia, Spain

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Pamplona, Spain

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Santander, Spain

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Valladolid, Spain

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Zaragoza, Spain

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Bern, Switzerland

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Zurich, Switzerland

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Kaohsiung, Taiwan

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Taichung, Taiwan

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Tainan, Taiwan

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Taipei, Taiwan

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Taoyuan, Taiwan

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London, United Kingdom

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Guildford, United Kingdom

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Bristol, United Kingdom

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Edinburgh, United Kingdom

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Birmingham, AL United States

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Iowa City, IA United States

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Musashino-shi, Japan

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Houston, TX United States

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Matsuyama-shi, Japan

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Yokohama, Japan

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Chiba, Japan

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Tampa, FL United States

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Pittsburgh, PA United States

Recruitment Status: Open

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