A Randomized Unblinded Feasibility Study Evaluating the Use of Oral Administration of MB-102 versus Dual Sugar Testing for Gut Permeability in Normal Subjects and Subjects with Active Small Bowel Crohn's Disease

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Updated on 22 September 2021

Summary

This is a phase I feasibility study to evaluate the use of MB-102 as a means to test intestinal permeability (the ability of a substance to allow another substance to pass through it). MB-102 has critical similarities to the compounds used in dual sugar testing; mainly molecular weight and excretion exclusively via glomerular filtration (the first step in making urine).
An evaluation that compares the spectrum of MB-102 excreted in normal subjects and subject's with active Crohn's disease vs results obtained from those same subjects undergoing dual sugar testing will determine if further development of MB-102 and a sensor device to detect skin fluorescence is feasible in this indication.
 

Description


Details
Condition *Healthy Volunteers
Clinical Study IdentifierTX228538
Last Modified on22 September 2021

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